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Development of Multiplex Real-Time RT-qPCR Assays for the Detection of SARS-CoV-2, Influenza A/B, and MERS-CoV
Published on: November 10, 2023
Insights into the ecological and climate crisis: Emerging infections threatening human health
Francesco Vladimiro Segala1, Giacomo Guido1, Giacomo Stroffolini2
1Clinic of Infectious Diseases, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", 70124 Bari, Italy.
Abstract:
The Anthropocene era is marked by unprecedented human-induced alterations to the environment, resulting in a climate emergency and widespread ecological deterioration. A staggering number of up to one million species of plants and animals are in danger of becoming extinct, which includes over 10 % of insect species and 40 % of plant species. Unrestrained release of greenhouse gases, widespread deforestation, intense agricultural practices, excessive fishing, and alterations in land use have exceeded the ecological boundaries that were once responsible for humanity's wellbeing. As per the Intergovernmental Panel on Climate Change (IPCC), existing policies are expected to result in a minimum rise in global temperature of +2 °C, with more recent assessments indicating a potential increase of up to +2.9 °C. The effects of climate change and ecological degradation on the formation of diseases are complex and have multiple aspects. Deforestation diminishes biodiversity and compels wildlife to come into greater proximity with humans, hence promoting the transmission of zoonotic diseases. Climate change intensifies these impacts by modifying the habitats of disease carrying organisms, resulting in the expansion of vector-borne diseases such as malaria, dengue, and Zika virus into previously unaffected areas. Furthermore, climate change amplifies the occurrence and severity of extreme weather phenomena, which undermines water, sanitation, and hygiene (WASH) practices. This creates an environment conducive to the transmission of waterborne diseases such as cholera in densely populated resettlement camps. Climate-induced disasters contribute to the complexity of epidemiological landscapes, exacerbating antimicrobial resistance and posing a threat to modern medical advancements. This narrative review investigates the complex connections between the ecological-climatic crises and emerging illnesses, offering an overview on how environmental changes contribute to outbreaks that pose a substantial threat to public health.
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