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08:46
Implementation of In Vitro Drug Resistance Assays: Maximizing the Potential for Uncovering Clinically Relevant Resistance Mechanisms
Published on: December 9, 2015
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Pharmacological Approaches and Innovative Strategies for Individualized Patient Care.
Amnesh Kumar Verma1, Kuldeep Singh1, Jeetendra Kumar Gupta1
1Department of Pharmacology, Institute of Pharmaceutical Research, GLA University, Mathura, Uttar Pradesh, India.
Recent Patents on Biotechnology
|January 22, 2025
Summary
Personalized medicine tailors treatments using genomics and other
Area of Science:
- Biomedical Sciences
- Pharmacology
- Genetics
Background:
- Personalized medicine revolutionizes healthcare by tailoring treatments to individual patient characteristics.
- Advances in understanding genetic, epigenetic, and molecular disease mechanisms enable more effective, tailored therapies.
Purpose of the Study:
- This review highlights advancements in personalized medicine, focusing on pharmacological strategies.
- It explores the integration of multi-omics data and computational tools for optimizing drug therapy.
- The review emphasizes pharmacogenomics for predicting therapeutic response and toxicity.
Main Methods:
- Review of current literature on personalized medicine and pharmacogenomics.
- Integration of genomics, transcriptomics, proteomics, and metabolomics in drug development.
- Application of computational tools and artificial intelligence in treatment planning.
Main Results:
- Pharmacogenomics enables customized drug therapy based on genetic makeup.
- Biomarkers are identified for predicting treatment efficacy, drug toxicity, and disease susceptibility.
- Tailored treatment plans are developed for complex diseases like cancer and neurological disorders.
Conclusions:
- Personalized medicine, driven by pharmacogenomics and multi-omics, enhances therapeutic outcomes.
- Challenges include data privacy, cost, and accessibility, requiring collaborative efforts.
- Future research and interdisciplinary collaboration are crucial for advancing personalized medicine.
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