Prevalence of lymphedema symptoms across cancer diagnoses and association with depression, pain interference and health-related quality of life
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View abstract on PubMed
Summary
This summary is machine-generated.Lymphedema symptoms are common after cancer treatment, affecting diverse diagnoses. These symptoms significantly correlate with increased depression, pain, and reduced quality of life.
Area Of Science
- Oncology
- Clinical Research
- Patient Outcomes
Background
- Lymphedema is a frequent, yet understudied, complication following cancer therapy.
- Its prevalence across various cancer types and its impact on patient well-being require further investigation.
Purpose Of The Study
- To determine the prevalence of lymphedema symptoms in patients with different cancer diagnoses.
- To analyze the association between lymphedema symptoms and depression, pain interference, and health-related quality of life (HRQoL).
Main Methods
- Cross-sectional study at Copenhagen University Hospital involving 1,296 patients in follow-up.
- Online assessment of lymphedema symptoms (swelling, heaviness, tightness).
- Utilized validated questionnaires for HRQoL, depression, and pain interference; analyzed associations using multiple linear regression.
Main Results
- One-third of patients (33%) reported lymphedema symptoms, with 38% of those experiencing moderate/severe symptoms.
- Gynecological cancer patients reported the highest prevalence (59%), followed by head/neck (41%), breast (21%), and testicular (19%).
- Moderate/severe lymphedema symptoms were linked to higher depression and pain interference, and lower HRQoL.
Conclusions
- Lymphedema symptoms are prevalent in survivors of various cancers.
- These symptoms are significantly associated with adverse psychological and physical health outcomes, including depression, pain, and diminished HRQoL.
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