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Updated: Jun 1, 2025

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Persistent Gingival Bleeding Related to Periodontal Disease
Yosuke Iijima1, Miki Yamada1, Takumi Takahashi1
1Department of Oral and Maxillofacial Surgery, Saitama Medical Center, Saitama Medical University, Saitama, JPN.
Persistent gingival bleeding (PGB) linked to periodontal disease (PD) is common in older adults, especially those on blood thinners or with hypertension. Regular dental care is crucial for prevention.
Area of Science:
- Oral Surgery
- Periodontology
- Internal Medicine
Background:
- Persistent gingival bleeding (PGB) related to periodontal disease (PD) is a frequent reason for evening and night visits to oral surgery clinics.
- Limited characterization exists for PD-PGB, necessitating detailed investigation.
Purpose of the Study:
- To conduct a detailed characterization of patients presenting with persistent gingival bleeding (PGB) associated with periodontal disease (PD).
- To identify demographic, systemic, and clinical factors associated with PD-PGB.
Main Methods:
- Retrospective analysis of 295 patients with non-traumatic gingival bleeding (GB) treated between January 2014 and December 2022.
- Demographic data, systemic diseases, and bleeding characteristics were collected.
- Comparison with a control group (temporomandibular joint dislocation and minor trauma patients).
Main Results:
- 91 patients (30.1%) were diagnosed with PD-PGB.
- PD-PGB was prevalent in 93.4% of patients over 60 years old.
- Patients with PD-PGB had higher rates of anticoagulant/antiplatelet use (57.1% vs 24.2%) and hypertension (68.1% vs 34.1%) compared to controls.
- Bleeding primarily occurred in molars with pocket depths exceeding 4 mm.
Conclusions:
- PD-PGB, particularly with deep periodontal pockets, is more common in older individuals.
- Anticoagulant/antiplatelet therapy and hypertension significantly aggravate PD-PGB.
- PD-PGB is not rare; periodontal maintenance and regular dental check-ups are vital preventive strategies.
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