Higher triglyceride-glucose index and triglyceride glucose-body mass index protect against sarcopenia in Chinese middle-aged and older non-diabetic women: a cross-sectional study
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View abstract on PubMed
Summary
This summary is machine-generated.Higher triglyceride-glucose (TyG) index and TyG-body mass index (BMI) are linked to a lower risk of sarcopenia in older women. TyG-BMI is a reliable indicator for predicting sarcopenia.
Area Of Science
- Gerontology
- Metabolic Health
- Sarcopenia Research
Background
- Sarcopenia is a significant health concern in aging populations, often undertreated.
- Understanding metabolic indicators for sarcopenia is crucial for early intervention.
Purpose Of The Study
- To explore the association between the triglyceride-glucose (TyG) index, TyG-body mass index (BMI), and sarcopenia in non-diabetic women aged 50 and above.
- To determine if TyG index and TyG-BMI can serve as predictive markers for sarcopenia.
Main Methods
- A cross-sectional study involving 460 non-diabetic postmenopausal women aged ≥50 years.
- Analysis of correlations between TyG index, TyG-BMI, and sarcopenia prevalence.
- Multivariate analysis and receiver operating characteristic (ROC) curve analysis were performed.
Main Results
- Increased TyG index and TyG-BMI were associated with a decreased prevalence of sarcopenia.
- Both TyG index and TyG-BMI showed an inverse relationship with sarcopenia.
- The TyG-BMI index demonstrated a high diagnostic accuracy (AUC: 0.858) for sarcopenia.
Conclusions
- Elevated TyG index and TyG-BMI confer a protective effect against sarcopenia in non-diabetic middle-aged and older women.
- The TyG-BMI index is identified as a dependable and cost-effective biomarker for sarcopenia prediction.
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