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Inflammatory Bowel Disease V: Surgical Management

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:

Assessment of the Rectum and Anus

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...

Drugs for Treatment of Constipation-Predominant IBS

Drugs for Treatment of Constipation-Predominant IBS

Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...

Drugs for Treatment of Diarrhea-Predominant IBS

Drugs for Treatment of Diarrhea-Predominant IBS

Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...

Irritable Bowel Syndrome III: Medical and Nursing Management

Irritable Bowel Syndrome III: Medical and Nursing Management

Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.

Inflammatory Bowel Disease I: Ulcerative Colitis

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...

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Related Experiment Video

Updated: Jun 1, 2025

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

Controversies in fecal incontinence.

Andreia Albuquerque^1,2, Satish S C Rao³

¹School of Medicine and Biomedical Sciences, Fernando Pessoa University, Gondomar 4420-096, Porto, Portugal.

World Journal of Gastroenterology

|January 22, 2025

Summary

Fecal incontinence significantly impacts quality of life. Novel diagnostic and treatment options, including neuromodulation and cell implantation, show promise for managing this condition.

Keywords:

Anal sphincter defects Biofeedback Endoanal ultrasound Fecal incontinence Neuropathy Sacral neuromodulation

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Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

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Published on: December 8, 2014

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model

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A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

Area of Science:

Gastroenterology and Colorectal Surgery
Pelvic Floor Disorders
Neuromodulation Therapies

Background:

Fecal incontinence (FI) is a prevalent condition with significant quality of life implications.
Common causes include obstetric anal sphincter injury and anorectal surgeries.
Endoanal ultrasound and anorectal manometry are key diagnostic tools.

Discussion:

Current controversies involve screening for asymptomatic anal sphincter defects.
Novel diagnostic tools like translumbosacral anorectal magnetic stimulation are emerging.
Home biofeedback therapy offers an alternative to office-based treatments.

Key Insights:

The Garg incontinence score provides a comprehensive assessment of FI symptoms.
Translumbosacral neuromodulation therapy presents a promising novel treatment.
Skeletal muscle-derived cell implantation is being investigated for external anal sphincter repair.

Outlook:

Sacral neuromodulation shows potential for specific conditions like scleroderma and inflammatory bowel disease-related FI.
Further research is needed for translumbosacral neuromodulation and cell implantation therapies.
Advancements in diagnostics and therapies aim to improve fecal incontinence management.