Related Experiment Video
Updated: Jun 1, 2025

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
Published on: December 8, 2014
Controversies in fecal incontinence
Andreia Albuquerque1,2, Satish S C Rao3
1School of Medicine and Biomedical Sciences, Fernando Pessoa University, Gondomar 4420-096, Porto, Portugal.
Fecal incontinence significantly impacts quality of life. Novel diagnostic and treatment options, including neuromodulation and cell implantation, show promise for managing this condition.
Area of Science:
- Gastroenterology and Colorectal Surgery
- Pelvic Floor Disorders
- Neuromodulation Therapies
Background:
- Fecal incontinence (FI) is a prevalent condition with significant quality of life implications.
- Common causes include obstetric anal sphincter injury and anorectal surgeries.
- Endoanal ultrasound and anorectal manometry are key diagnostic tools.
Discussion:
- Current controversies involve screening for asymptomatic anal sphincter defects.
- Novel diagnostic tools like translumbosacral anorectal magnetic stimulation are emerging.
- Home biofeedback therapy offers an alternative to office-based treatments.
Key Insights:
- The Garg incontinence score provides a comprehensive assessment of FI symptoms.
- Translumbosacral neuromodulation therapy presents a promising novel treatment.
- Skeletal muscle-derived cell implantation is being investigated for external anal sphincter repair.
Outlook:
- Sacral neuromodulation shows potential for specific conditions like scleroderma and inflammatory bowel disease-related FI.
- Further research is needed for translumbosacral neuromodulation and cell implantation therapies.
- Advancements in diagnostics and therapies aim to improve fecal incontinence management.
Related Concept Videos
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Assessment of the Rectum and Anus
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Drugs for Treatment of Constipation-Predominant IBS
Drugs for Treatment of Diarrhea-Predominant IBS
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Irritable Bowel Syndrome III: Medical and Nursing Management
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...

