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Updated: Jun 1, 2025
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In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
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How to perform and evaluate a myocardial perfusion imaging by computed tomography
Saima Mushtaq1, Andrea Baggiano1, Francesco Cannata1
1Perioperative Cardiology and Cardiovascular Imaging Department, Centro Cardiologico Monzino IRCCS, Via C. Parea 4, Milan 20138, Italy.
European Heart Journal. Imaging Methods and Practice
|January 22, 2025
Summary
Stress computed tomography perfusion (CTP) offers a non-invasive way to assess coronary artery disease (CAD) by evaluating both anatomy and function. This review guides CTP use for diagnosing and managing CAD patients.
Area of Science:
- Cardiovascular imaging
- Radiology
- Medical diagnostics
Background:
- Coronary artery disease (CAD) requires accurate diagnostic tools.
- Current methods may not fully integrate anatomical and functional assessments.
- Non-invasive quantification of coronary stenosis and its impact is crucial.
Purpose of the Study:
- To provide a practical guide on conducting and interpreting stress computed tomography perfusion (CTP).
- To highlight CTP as a comprehensive, non-invasive tool for CAD evaluation.
- To analyze the strengths and limitations of static and dynamic CTP.
Main Methods:
- Review of static and dynamic stress computed tomography perfusion (CTP) methodologies.
- Guidance on CTP acquisition and interpretation.
- Analysis of CTP's diagnostic and management capabilities in CAD.
Main Results:
- CTP integrates anatomical and functional assessment in a single examination.
- CTP is the sole non-invasive technique for quantifying coronary stenosis and functional impact.
- Provides a consolidated approach for CAD diagnosis and management.
Conclusions:
- Stress CTP is a valuable, non-invasive tool for comprehensive CAD assessment.
- CTP facilitates improved diagnostic accuracy and patient management strategies.
- Understanding CTP's strengths and limitations is key for optimal clinical application.
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