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Herbal Medicines as Complementary Therapy for Managing Complications in COVID-19 Patients with Diabetes Mellitus

Syah Akbarul Adha1, Nadiya Nurul Afifah1,2, Irma Rahayu Latarissa3,4

  • 1Department of Biological Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia.

Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy
|January 22, 2025
PubMed

Insights

Several herbal medicines show potential as complementary treatments for COVID-19 complications in Diabetes Mellitus patients. Further research is needed to validate these findings in clinical settings.

Area of Science:

  • Integrative Medicine
  • Pharmacology
  • Immunology

Background:

  • Diabetes Mellitus (DM) is characterized by hyperglycemia and inflammation, increasing susceptibility to infections like Coronavirus Disease 2019 (COVID-19).
  • Effective treatments for COVID-19 in DM patients are lacking, highlighting the need for novel therapeutic strategies.
  • Herbal medicines possess diverse pharmacological properties, including antidiabetic, antiviral, and anti-inflammatory effects, making them candidates for complementary therapy.

Purpose of the Study:

  • To investigate the potential of herbal medicines as complementary therapies for Diabetes Mellitus patients experiencing COVID-19 complications.
  • To review existing in-vitro and in-vivo evidence on the efficacy of various medicinal plants.

Main Methods:

  • A literature review was conducted, analyzing articles published within the last 15 years.
  • Keywords used included 'herbal medicines', 'COVID-19', 'Diabetes Mellitus', 'antidiabetics', 'antiviral', and 'anti-inflammatory'.

Main Results:

  • Ten specific herbal medicines demonstrated potential as complementary treatments: Andrographis paniculata, Ageratum conyzoides, Artocarpus altilis, Centella asiatica, Momordica charantia, Persea gratissima, Phyllanthus urinaria, Physalis angulata, Tinospora cordifolia, and Zingiber zerumbet.
  • These herbs exhibited relevant antidiabetic, antiviral, and anti-inflammatory properties.

Conclusions:

  • Herbal medicines may offer a complementary therapeutic approach for managing COVID-19 in Diabetes Mellitus patients.
  • Experimental validation in infection models and clinical trials is essential to confirm the efficacy and safety of these herbal remedies.

Keywords:
COVID-19anti-inflammatoryantidiabeticdiabetes mellitusherbal medicinesimmunomodulator

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