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SURGICAL TECHNIQUES TO INCREASE RESECTABILITY IN LIVER METASTASIS
Orlando Jorge Martins Torres1, Guido Torzilli2, Marcelo Enne3
1Hepatopancreatobiliary Surgery and Liver Transplant, Department of Gastrointestinal Surgery - São Luís (MA), Brazil.
Summary
Advanced treatments now allow surgery for unresectable colorectal liver metastases. Various strategies enable resection, offering the only curative option for this disease.
Area of Science:
- Hepatobiliary Surgery
- Surgical Oncology
- Gastroenterology
Background:
- Colorectal liver metastases (CLM) are a significant cause of cancer mortality.
- Historically, unresectable CLM had limited treatment options.
- Multidisciplinary advancements have shifted the paradigm for CLM management.
Purpose of the Study:
- To review the evolving surgical strategies for patients with initially unresectable colorectal liver metastases.
- To highlight the curative potential of surgical resection in managing CLM.
Main Methods:
- Review of contemporary surgical techniques and neoadjuvant therapies.
- Analysis of strategies enabling liver resection for unresectable CLM.
- Discussion of multidisciplinary care in CLM treatment.
Main Results:
- Surgical techniques, chemotherapy, and biological agents have expanded eligibility for surgery.
- Several strategies facilitate liver resection, including portal vein embolization and staged hepatectomy.
- Surgical resection remains the sole curative treatment for CLM.
Conclusions:
- Patients with unresectable CLM can now be considered for surgical resection.
- A range of innovative surgical approaches enables curative treatment.
- Multidisciplinary management is crucial for optimizing outcomes in CLM.
