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  11. Treatment, Prognosis, And Outcome Of Dogs Treated For Rectal Plasmacytoma: A Multicentric Retrospective Study

Treatment, prognosis, and outcome of dogs treated for rectal plasmacytoma: a multicentric retrospective study

Juan Carlos Jimeno Sandoval1, Matteo Cantatore1, Lee Meakin2

  • 11Anderson Moores Veterinary Specialists, Winchester, UK.

Journal of the American Veterinary Medical Association
|January 22, 2025

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View abstract on PubMed

Summary
This summary is machine-generated.

Surgical treatment for canine rectal plasmacytomas offers long survival with low major complications. However, recurrence and metastasis rates are higher than previously reported, warranting further research into adjuvant therapies.

Area of Science:

  • Veterinary Oncology
  • Surgical Pathology

Background:

  • Rectal plasmacytomas are uncommon canine tumors.
  • Understanding treatment outcomes and prognostic factors is crucial for effective management.

Purpose of the Study:

  • To evaluate the outcomes and prognosis of dogs with rectal plasmacytomas treated surgically or medically.
  • To identify factors influencing recurrence, mortality, and progression to multiple myeloma.

Main Methods:

  • Retrospective review of 20 canine cases from 7 referral hospitals.
  • Kaplan-Meier and Cox proportional hazards analyses were used for outcome assessment.

Main Results:

  • Nineteen dogs underwent surgery; one received conservative management.
  • Metastasis occurred in 10% of cases; recurrence in 31.5% of surgically treated dogs.
Keywords:
dogplasmacytomarectaltreatment

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  • One- and three-year survival rates were 95% and 66%, respectively. No cases progressed to multiple myeloma.

    • Conclusions:

    • Surgical intervention for rectal plasmacytomas yields favorable long-term survival with minimal major complications.
    • Higher than expected rates of metastasis and recurrence were observed, suggesting a need for adjuvant treatment strategies.
    tumor