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Updated: May 31, 2025

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
Confocal Reflectance Microscopy Findings in Juvenile Xanthogranuloma: Report of 2 Cases
Lynn Midani1, Katherine Park2, Shelly Stepenaskie2,3
1University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.
Abstract:
Juvenile xanthogranuloma (JXG) is the most common type of non-Langerhans cell histiocytosis and is characterized by a benign proliferation of dermal dendrocytes. We report two children diagnosed with JXG with reflectance confocal microscopy (RCM), a noninvasive imaging technology that allows for multi-layer visualization of the skin. This report demonstrates the emerging role of RCM as a painless diagnostic aid for JXG and other cutaneous diseases in children.
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