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Updated: May 31, 2025

Live-Cell Imaging of the Life Cycle of Bacterial Predator Bdellovibrio bacteriovorus using Time-Lapse Fluorescence Microscopy
Published on: May 8, 2020
How do Gram-negative bacteria escape predation by Bdellovibrio bacteriovorus?
Sourav Kumar Das1, David Negus2
1Department of Biosciences, Nottingham Trent University, Nottingham, UK.
Abstract:
Bdellovibrio bacteriovorus is a small predatory bacterium which reproduces by invading and killing Gram-negative bacteria. The natural antimicrobial activity of B. bacteriovorus has garnered interest for the potential to develop this predatory bacterium as a therapeutic agent. Transitioning B. bacteriovorus from 'bench to bedside' will require a complete understanding of all aspects of bacterial predation, including how prey species may escape predation. Here we discuss recent findings relating to how Gram-negative bacteria may escape predation.
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