Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Decreased Body Temperature01:29

Decreased Body Temperature

602
A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by...
602
Increased Body Temperature01:25

Increased Body Temperature

639
A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
639

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Figure-of-eights vs running suture for fascial closure of large ventral hernias: do figure-of-eights induce ischemia?

Surgical endoscopy·2026
Same author

Characterizing bleeding risk of extracorporeal limb salvage with concomitant vascular injury.

The journal of trauma and acute care surgery·2026
Same author

Etiology of Limb Loss after Successful Transmetatarsal Amputation.

Annals of vascular surgery·2026
Same author

Emergency preservation and resuscitation in exsanguination cardiac arrest: science fiction to future reality?

Trauma surgery & acute care open·2026
Same author

Selective aortic arch perfusion vs. conventional advanced cardiac life support: a bi-ventricular pressure-volume loop analysis in a swine model of cardiac arrest.

Resuscitation plus·2026
Same author

Time Is of the Essence: Impact of Transfer on Outcomes in Acute Mesenteric Ischemia.

Journal of the American College of Surgeons·2025
Same journal

Are the Charlson and Elixhauser comorbidity indices reliable predictors of postoperative delirium in abdominal surgery?

Surgery in practice and science·2026
Same journal

Traumatic diaphragmatic hernia: A 38-case retrospective analysis of presentation and outcomes.

Surgery in practice and science·2026
Same journal

Trend and cost analysis comparing laparoscopic versus open liver resections at a Tertiary Referral hospital in Australia.

Surgery in practice and science·2026
Same journal

Commentary on: Artificial intelligence in thoracic surgery: Perspectives and challenges.

Surgery in practice and science·2026
Same journal

Plasma fibrinogen: A novel biomarker for preoperative prediction and quantification of peritoneal adhesions in emergency abdominal surgery.

Surgery in practice and science·2026
Same journal

Combined Impact of Cannabinoids and Cocaine on Outcomes of Trauma Patients.

Surgery in practice and science·2026
See all related articles

Related Experiment Video

Updated: May 31, 2025

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms
05:00

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms

Published on: March 3, 2021

2.9K

High flow cooled air can decrease brain temperature without injuring the snout or brain in Swine.

David P Stonko1,2, Michael J Richmond3, Joseph Edwards3

  • 1Department of Surgery, Johns Hopkins Hospital, Baltimore, MD, USA.

Surgery in Practice and Science
|January 23, 2025
PubMed
Summary
This summary is machine-generated.

A new intranasal cooled air device effectively lowers brain temperature in a large animal model. This non-invasive method shows promise for targeted temperature management in critical illnesses without causing injury.

Keywords:
Brain traumaCNS injuryIsolated brain coolingNeurocritical careTemperature management

More Related Videos

Intubation, Central Venous Catheter, and Arterial Line Placement in Swine for Translational Research in Abdominal Transplantation Surgery
06:33

Intubation, Central Venous Catheter, and Arterial Line Placement in Swine for Translational Research in Abdominal Transplantation Surgery

Published on: February 3, 2023

1.2K
Direct Cannula Implantation in the Cisterna Magna of Pigs
08:06

Direct Cannula Implantation in the Cisterna Magna of Pigs

Published on: June 9, 2021

3.7K

Related Experiment Videos

Last Updated: May 31, 2025

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms
05:00

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms

Published on: March 3, 2021

2.9K
Intubation, Central Venous Catheter, and Arterial Line Placement in Swine for Translational Research in Abdominal Transplantation Surgery
06:33

Intubation, Central Venous Catheter, and Arterial Line Placement in Swine for Translational Research in Abdominal Transplantation Surgery

Published on: February 3, 2023

1.2K
Direct Cannula Implantation in the Cisterna Magna of Pigs
08:06

Direct Cannula Implantation in the Cisterna Magna of Pigs

Published on: June 9, 2021

3.7K

Area of Science:

  • Critical Care Medicine
  • Medical Devices
  • Neuroscience

Background:

  • Targeted temperature management is crucial for treating critical illnesses.
  • Current non-invasive methods for isolated brain temperature control are limited.
  • A need exists for rapid and localized cooling solutions.

Purpose of the Study:

  • To evaluate the safety and efficacy of a novel intranasal high flow cooled air device.
  • To assess the device's ability to achieve isolated brain and head cooling.
  • To determine the potential for injury associated with the device.

Main Methods:

  • Yorkshire swine were instrumented with temperature probes (rectum, brain, ear, snout).
  • A novel intranasal cooled air device was applied to half the animals.
  • Outcomes included brain, snout, and tympanic temperature changes, and assessment for injury via CT and histology.

Main Results:

  • Intranasal, intracranial, and tympanic temperatures significantly decreased during cooling.
  • Rectal temperature remained unchanged, indicating localized cooling.
  • No short- or medium-term injury was observed in the snout, CT perfusion, or histology.

Conclusions:

  • The novel intranasal cooled air device is safe and effective for isolated brain and head cooling.
  • This non-invasive technology offers a promising approach for targeted temperature management.
  • Further research may explore its clinical applications in critical care.