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Updated: May 31, 2025

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
Motor mapping-guided resection of a brainstem recurrent pilocytic astrocytoma
Xiaopeng Guo1,2, Mitali Bose3, Colin Patrick Galvin1
1Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Abstract:
Brainstem tumors are bounded by a compact topography of eloquent tracts, cranial nerves, and nuclei. Reliable intraoperative neuromonitoring aids microneurosurgical technique to optimize safe resection. The authors present a case of motor mapping-guided resection of a recurrent brainstem pilocytic astrocytoma. They demonstrate reliable and continuous responses from the corticospinal tract at the level of the midbrain to the pons with dynamic subcortical motor mapping using a monopolar stimulating suction. Contralateral limb and ipsilateral face muscles can be simultaneously detected and tumor resected until a threshold of less than 1 mA, corresponding to 1 mm or less from the corticospinal tracts. The video can be found here: https://stream.cadmore.media/r10.3171/2024.10.FOCVID24110.
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