Related Experiment Video
Updated: Sep 6, 2026
Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting
Published on: March 25, 2019
Nanoparticles in gynecologic cancers: a bibliometric and visualization analysis
Yunzhe Zhou1, Lizhang Chen1, Tingting Wang1
1Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, China.
Background:
Gynecological cancers are characterized by uncontrolled cell proliferation within the female reproductive organs. These cancers pose a significant threat to women's health, impacting life expectancy, quality of life, and fertility. Nanoparticles, with their small size, large surface area, and high permeability, have become a key focus in targeted cancer therapy. The aim of this study is to review recent advancements in nanoparticles applied to gynecologic cancers, providing valuable insights for future research.
Methods:
We retrieved all literature on nanoparticles in gynecologic cancers from the Web of Science Core Collection (WOSCC) database between January 1, 2004, and June 4, 2024. Data analysis and visualization were conducted using R software (version 4.4.0), VOSviewer (version 1.6.19.0), and CiteSpace (version 6.1).
Results:
A total of 2,843 publications from January 1, 2004, to June 4, 2024 were searched. Over the past 20 years, there has been a significant increase in publications. The leading countries and institutions in terms of productivity are China and the Chinese Academy of Sciences. The most prolific author and the most co-cited author are Sood, A K and Siegel, Rl. The top journals are the International Journal of Nanomedicine (n=97), followed by ACS Applied Materials & Interfaces (n=72) and Journal of Materials Chemistry B (n=53). Keyword analysis shows current research focuses on two main areas: the application of nanoparticles for drug delivery and their broader applications in gynecologic cancers. Future research will likely focus on "silver nanoparticles," "gold nanoparticles," and "green synthesis."
Conclusions:
Over the past two decades, nanoparticles have rapidly advanced in the field of gynecologic cancers. Research has primarily focused on the applications of nanoparticles in drug delivery and applications. Future trends point toward optimizing synthesis techniques and advancing preclinical studies to clinical applications, particularly for silver and gold nanoparticles. These findings provide valuable scientific insights for researchers.
Insights
Nanoparticles show significant advancements in treating gynecologic cancers, focusing on drug delivery and broader applications. Future research will explore silver and gold nanoparticles for enhanced cancer therapy.
Area of Science:
- Biomedical Engineering
- Nanotechnology
- Oncology
Background:
- Gynecological cancers are a major threat to women's health, affecting lifespan, quality of life, and fertility.
- Nanoparticles offer unique properties like small size and high permeability, making them promising for targeted cancer therapy.
- This review examines recent progress in nanoparticle applications for gynecologic cancers.
Purpose of the Study:
- To review and analyze the recent advancements in nanoparticle applications for gynecologic cancers.
- To identify key research trends, leading contributors, and influential publications in the field.
- To provide insights for future research directions in nanoparticle-based gynecologic cancer treatment.
Main Methods:
- A comprehensive literature search was conducted on the Web of Science Core Collection (WOSCC) from 2004 to 2024.
- Bibliometric analysis and data visualization were performed using R software, VOSviewer, and CiteSpace.
- A total of 2,843 publications were analyzed to identify research trends and key players.
Main Results:
- Publication output has significantly increased over the last two decades.
- China and the Chinese Academy of Sciences are leading in productivity, with Sood, A K and Siegel, Rl as prominent authors.
- Key research areas include nanoparticle drug delivery and broader applications, with future focus on silver nanoparticles, gold nanoparticles, and green synthesis.
Conclusions:
- Nanoparticle research in gynecologic cancers has rapidly advanced over the past 20 years.
- Current research emphasizes drug delivery and applications, with a growing interest in silver and gold nanoparticles.
- Future efforts should focus on optimizing synthesis and progressing from preclinical to clinical applications.
