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SWEET'S SYNDROME ASSOCIATED WITH PHEOCHROMOCYTOMA: A RARE CASE REPORT AND REVIEW OF LITERATURE
M I Chiriac Bozac1, S A Big2, R A Maxim3
1"Iuliu Hațieganu" University of Medicine and Pharmacy - Discipline of Endocrinology, 6th Medical Specialties Department.
Acta Endocrinologica (Bucharest, Romania : 2005)
|January 23, 2025
Summary
Sweet's syndrome, a rare dermatosis, can be linked to pheochromocytoma. Surgical removal of the adrenal tumor led to the resolution of skin lesions in a recent case.
Area of Science:
- Dermatology
- Endocrinology
- Oncology
Background:
- Sweet's syndrome (acute febrile neutrophilic dermatosis) presents with fever and tender skin lesions.
- It has three subclasses: classical, malignancy-associated, and drug-induced.
- The syndrome can indicate underlying hematological or solid malignancies.
Observation:
- A 55-year-old female presented with mucocutaneous lesions and aphthous ulcers, preceded by fever and chills.
- Imaging revealed a right adrenal pheochromocytoma with elevated normetanephrines.
- The patient underwent laparoscopic adrenalectomy after alpha-blocker therapy.
Findings:
- This case highlights a rare association between Sweet's syndrome and pheochromocytoma.
- Surgical intervention for pheochromocytoma resulted in favorable clinical outcomes.
- Cutaneous lesions of Sweet's syndrome began healing post-adrenalectomy.
Implications:
- This case underscores the importance of investigating potential underlying conditions, such as pheochromocytoma, in patients with Sweet's syndrome.
- Multidisciplinary collaboration is crucial for managing rare associations like Sweet's syndrome and pheochromocytoma.
- Early diagnosis and treatment of pheochromocytoma can lead to the resolution of associated dermatological manifestations.
Keywords:
Sweet's syndromeacute febrile neutrophilic dermatosislaparoscopic adrenalectomypheochromocytomaMore Related Videos
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