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Alfred Adler, a prominent figure in psychology, founded the school of individual psychology. In contrast to Freud's emphasis on sexual or aggressive motives, Adler suggested that individuals are primarily motivated by their purposes and goals. He believed that people strive for perfection rather than pleasure. Adler argued that individuals could creatively act upon their genetic inheritance and environmental experiences to shape their own lives, emphasizing conscious motivation over...
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Related Experiment Video

Updated: May 31, 2025

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Navigating Hope and Complexity: Turkish Parents’ Experiences with Savior Siblings

İbrahim Eker1, Hamide Nur Çevik Özdemir2, Fırat Yılmaz3

  • 1Afyonkarahisar Health Sciences University Faculty of Medicine, Department of Pediatric Hematology and Oncology and Pediatric Hematopoietic Stem Cell Transplantation Unit, Afyon, Türkiye

Turkish Journal of Haematology : Official Journal of Turkish Society of Haematology
|January 23, 2025
PubMed
Summary

Turkish parents navigated the emotional and practical challenges of savior sibling procedures for thalassemia major treatment. Despite difficulties, they showed resilience, supported by family and healthcare, highlighting the need for culturally sensitive support.

Keywords:
Savior siblingsTurkish familiesPreimplantation genetic diagnosisStem cell transplantationQualitative researchMedical ethics

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Area of Science:

  • Medical Genetics
  • Hematology
  • Reproductive Medicine

Background:

  • Preimplantation genetic diagnosis (PGD) with human leukocyte antigen (HLA) typing enables the birth of healthy children who can act as stem cell donors.
  • Türkiye is a global leader in PGD+HLA typing and hematopoietic stem cell transplantation (HSCT) from savior siblings for inherited disorders like thalassemia major.

Purpose of the Study:

  • To investigate the medical, psychological, and sociocultural experiences of Turkish parents undergoing savior sibling procedures for thalassemia major treatment.
  • To understand the complexities of PGD+HLA typing and subsequent HSCT within the Turkish healthcare context.

Main Methods:

  • A qualitative descriptive phenomenological approach was used.
  • In-depth interviews were conducted with parents from 16 families who completed PGD+HLA matching and HSCT from a savior sibling.
  • Data analysis employed Colaizzi’s seven-step method and MAXQDA 20.0 software.

Main Results:

  • Six main themes emerged: disease stage, treatment, recovery, social/family dynamics, support systems, and recommendations.
  • Parents faced significant emotional challenges but displayed resilience, with religious and cultural factors playing nuanced roles.
  • Economic burdens, prolonged hospitalizations, and access to care were key challenges, while extended family and professional guidance were vital support.

Conclusions:

  • The study underscores the interplay of advanced medical technology and traditional values in Turkish society.
  • There is a critical need for comprehensive, culturally sensitive support systems and long-term follow-up for families undergoing these procedures.
  • Implementing multidisciplinary care teams and specialized support programs is recommended for families pursuing savior sibling treatments.