Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Discontinuing antiepileptic therapy.

R S Kandt, S K Bickley, L A Shimp

    American Family Physician
    |April 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Successful withdrawal of antiepileptic drugs is possible for carefully chosen patients. Maintaining therapy for at least three seizure-free years is recommended before discontinuing antiepileptics to minimize seizure recurrence risks.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    An assessment of home remedy use by African Americans.

    Journal of the National Medical Association·2000
    Same author

    Recent advances in geriatrics: drug-related problems in the elderly.

    The Annals of pharmacotherapy·2000
    Same author

    Tuberous Sclerosis Consensus Conference: recommendations for diagnostic evaluation. National Tuberous Sclerosis Association.

    Journal of child neurology·1999
    Same author

    Safety issues in the pharmacologic management of chronic pain in the elderly.

    Pharmacotherapy·1998
    Same author

    A novel splice site mutation (156 + 1G-->A) in the TSC2 gene.

    Human mutation·1997
    Same author

    Design and results of a group counter-detailing DUR educational program.

    Pharmaceutical research·1996

    Area of Science:

    • Neurology
    • Clinical Pharmacology

    Background:

    • Epilepsy management often involves long-term antiepileptic drug (AED) therapy.
    • Discontinuation of AEDs requires careful consideration of seizure recurrence risks and treatment benefits.

    Purpose of the Study:

    • To evaluate the prognosis for successful withdrawal of antiepileptic drugs in selected patients.
    • To identify key factors influencing the decision to discontinue AED therapy.

    Main Methods:

    • Review of existing studies and clinical guidelines on antiepileptic drug withdrawal.
    • Analysis of factors contributing to successful AED discontinuation and seizure recurrence.

    Main Results:

    • Excellent prognosis for AED withdrawal in carefully selected patient populations.

    Related Experiment Videos

  • Recommendation for a minimum of three years of seizure-free therapy before considering discontinuation.
  • Decision-making involves assessing seizure recurrence likelihood versus benefits of stopping medication.

    • Conclusions:

    • Successful antiepileptic drug withdrawal is achievable in appropriate patients.
    • A three-year seizure-free period is a critical benchmark for AED discontinuation.
    • Informed decisions require balancing the advantages of drug withdrawal against the risks of seizure recurrence.