Like, share, and spike: Glioblastoma progenitors influence neuronal excitability at the glioma-neural interface
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Updated: Jul 14, 2026

Isolation and Flow Cytometric Analysis of Glioma-infiltrating Peripheral Blood Mononuclear Cells
Published on: November 28, 2015
Christopher W Mount1, Mario L Suvà1
1Department of Pathology and Krantz Family Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.
Abstract:
Writing in Neuron, Zhang et al. identify a subpopulation of glioblastoma cells from patient tumor samples with progenitor-like features that expresses the potassium ion channel KCND2.1 In mouse and organoid models, these cells enhance neural activity at the glioma-neural interface.
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