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Postvagal tachycardia.

E N Prystowsky, D P Zipes

    The American Journal of Cardiology
    |April 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Post-vagal tachycardia, a rapid heart rate after enhanced vagal tone, occurs in some individuals. This phenomenon is not driven by beta-adrenergic activity but is blocked by muscarinic blockade.

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    Area of Science:

    • Cardiology
    • Autonomic Nervous System Physiology

    Background:

    • Vagal tone influences heart rate regulation.
    • Post-vagal tachycardia, a transient acceleration of heart rate after vagal stimulation, requires further investigation.

    Purpose of the Study:

    • To investigate the occurrence of post-vagal tachycardia.
    • To determine the role of autonomic blockade in modulating post-vagal tachycardia.

    Main Methods:

    • Enhanced vagal tone induced via neck suction in 21 patients.
    • Selective autonomic blockade using propranolol and atropine.
    • Sinus cycle length measured to assess heart rate changes.

    Main Results:

    • Neck suction significantly increased sinus cycle length, indicating vagal enhancement.

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  • Heart rate decreased significantly below control after neck suction cessation (postvagal tachycardia).
  • Propranolol did not alter postvagal tachycardia, while atropine prevented it.

    • Conclusions:

    • Post-vagal tachycardia is a distinct physiological response.
    • The response is not mediated by beta-adrenergic mechanisms.
    • Muscarinic blockade effectively inhibits post-vagal tachycardia.