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Updated: May 31, 2025

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease
Published on: May 9, 2022
Adjunctive therapea - a promising method in the treatment of periodontal disease
Viktoria Margaryan1, Eduard Aghasyan2, Lazar Yessayan3
1Department of Oral and Maxillofacial Surgery, Yerevan State Medical University, Yerevan, Armenia.
Objectives:
The aim of the study is to compare the clinical efficacy of the application of "Armenicum" paste as an adjunct to SRP for the non-surgical treatment of patients with periodontitis.
Methods:
The current RCT prospective study was conducted on 157 patients with chronic periodontitis. The patients were blind randomly assigned into two groups: Group A (SRP + Armenicum" paste) 81 patients (42 males and 39 females, 37 to 68 years) and Group B (SRP) 76 patients (39 males and 37 females, 37 to 68 years). Periodontal indices BOP, PPD, and DPI within each treatment group were measured before periodontal therapy, 3 and 6 months after the treatment. Group A underwent a periodontal treatment which included: supragingival and subgingival scaling, and additional use of local "Armenicum" paste. The Group B group only received supragingival and subgingival scaling.
Results:
In our study, the mean BOP, DPI, and PPD showed a statistically significant difference from baseline to 3 months and 6 months (p ≤ 0.05) in both Group A and Group B. But, mean BOP and mean PPD reduction gain was found to be greater in Group-A than Group B at 3 months and 6 months. No statistical differences in clinical indices were recorded depending on gender and age.
Conclusion:
These results indicate that topical "Armenicum" paste provides an effective adjunctive treatment of chronic periodontitis.
Clinical Relevance:
The results of the current study showed that the adjunctive use of "Armenicum" reduced signs of inflammation compared to standard SRP treatment alone. Periodontal therapy using Armenicum paste application can be considered as a promising method in the treatment of periodontitis.
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