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Elderly Onset Primary Intestinal Lymphangiectasia-A Rare Case.
Li-Han Goh1, Madhavan Manoharan2, Khean-Lee Goh3
1Faculty of Medicine, St Vincent's Clinical School The University of New South Wales Sydney New South Wales Australia.
JGH Open : an Open Access Journal of Gastroenterology and Hepatology
|January 24, 2025
Summary
Primary intestinal lymphangiectasia (PIL) is a rare condition causing protein loss. Diagnosis requires intestinal biopsies, and treatment involves dietary changes for clinical improvement.
Area of Science:
- Gastroenterology
- Vascular Biology
Background:
- Primary intestinal lymphangiectasia (PIL) is a rare protein-losing gastroenteropathy.
- Characterized by ectasia of enteric lymphatics, leading to hypoalbuminemia and lymphopenia.
- Diagnosis relies on endoscopic and histopathological examination due to lack of specific tests.
Purpose of the Study:
- To present a rare case of primary intestinal lymphangiectasia.
- To highlight diagnostic methods and treatment outcomes.
Main Methods:
- Endoscopic examination (gastroscopy and colonoscopy) with intestinal biopsies.
- Histopathological analysis of biopsy specimens.
- Exclusion of secondary causes of intestinal lymphangiectasia.
Main Results:
- A 62-year-old woman presented with lethargy, diarrhea, and weight loss.
- Biopsies revealed dilated intestinal lymphatics and broadened villi.
- Diagnosis of PIL confirmed after ruling out secondary causes.
Conclusions:
- Dietary management (high-protein, low-fat diet with medium-chain triglycerides) led to significant clinical improvement.
- Emphasizes the importance of biopsy in diagnosing PIL.
- Highlights successful management through dietary intervention.
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