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Updated: May 31, 2025

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
Published on: March 3, 2023
Risk of Colonization with Multidrug-Resistant Gram-Negative Bacteria Among Travellers and Migrants: A Narrative
Diogo Mendes Pedro1,2,3,4, Daniela Santos1, Maria Meneses1
1Laboratory of Microbiology Research in Environmental Health (EnviHealthMicro Lab), Institute of Environmental Health (ISAMB), Associate Laboratory TERRA, Faculdade de Medicina, Universidade de Lisboa, 1249-028 Lisboa, Portugal.
The rise of multidrug-resistant bacteria, particularly Gram-negative strains, is a global challenge amplified by travel and migration. Understanding resistance is crucial for public health strategies.
Area of Science:
- Microbiology
- Epidemiology
- Public Health
Background:
- 21st-century globalization facilitates the spread of infectious diseases.
- Multidrug-resistant (MDR) bacterial strains, especially Gram-negative bacteria, pose a significant global health threat.
- Increased international travel and migration exacerbate the dissemination of MDR bacteria.
Purpose of the Study:
- To highlight the critical issue of multidrug-resistant bacterial spread.
- To emphasize the public health risks associated with tourism and migration.
- To underscore the need for understanding resistance epidemiology and prevention.
Main Methods:
- Review of current literature on globalization and antimicrobial resistance.
- Analysis of epidemiological data concerning MDR Gram-negative bacteria.
- Examination of risk factors and public health implications.
Main Results:
- Globalization, tourism, and migration are key drivers for the spread of MDR bacteria.
- Transient colonization with MDR strains presents substantial health risks.
- High-risk bacterial clones are a growing concern in global public health.
Conclusions:
- Effective strategies are needed to curb the global spread of high-risk bacterial clones.
- Understanding resistance mechanisms and epidemiology is essential for prevention.
- Public health interventions must address the impact of globalization on infectious disease spread.
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