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Engineered Extracellular Vesicles Modified by Angiopep-2 Peptide Promote Targeted Repair of Spinal Cord Injury and

Guang Kong1, Jie Liu2, Juan Wang3

  • 1Department of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an 710000 Shaanxi, China.

ACS Nano
|January 24, 2025
PubMed
Summary

Engineered extracellular vesicles modified with Angiopep-2 peptide and melatonin effectively target spinal cord injury sites. These M-Ang2-EVs promote nerve repair, remyelination, and reduce both spinal cord and brain inflammation.

Keywords:
angiopep-2axonal regenerationcerebral inflammationengineered extracellular vesiclesmelatoninspinal cord injury

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