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Biological Sciences
Plant Biology
Phycology (incl. Marine Grasses)
Non-targeted Metabolomics-based Molecular Networking Enables The Chemical Characterization Of Rumex Sanguineus, A Wild Edible Plant.

Home
Research Domains
Biological Sciences
Plant Biology
Phycology (incl. Marine Grasses)
Non-targeted Metabolomics-based Molecular Networking Enables The Chemical Characterization Of Rumex Sanguineus, A Wild Edible Plant.

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Published on: January 7, 2019

Non-targeted metabolomics-based molecular networking enables the chemical characterization of Rumex sanguineus, a wild edible plant.

Valentina Ramundi^1,2,3,4, Mitja M Zdouc⁵, Enrica Donati²

¹Laboratory of Organic Chemistry, Wageningen University & Research, 6708 WE, Wageningen, the Netherlands.

Metabolomics : Official Journal of the Metabolomic Society

|January 24, 2025

View abstract on PubMed

Summary

This summary is machine-generated.

This study analyzed the chemical composition of Rumex sanguineus, identifying 347 metabolites, primarily polyphenols and anthraquinones. Emodin, a potentially toxic compound, was found in higher concentrations in the leaves, highlighting the need for careful analysis of medicinal plants used as food.

Keywords:

Emodin Feature-based molecular networking Metabolomics Polyphenols

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Area of Science:

Phytochemistry
Metabolomics
Plant Science

Background:

Rumex sanguineus is a traditional medicinal plant from the Polygonaceae family gaining popularity as an edible resource.
Its rich historical and nutritional significance is contrasted by a poorly understood chemical composition.

Purpose of the Study:

To conduct an in-depth analysis of Rumex sanguineus composition using non-targeted metabolomics.
To identify and quantify primary and specialized metabolites within the plant.

Main Methods:

Analysis of Rumex roots, stems, and leaves using Ultra-High-Performance Liquid Chromatography-High-Resolution Mass Spectrometry (UHPLC-HRMS).
Application of feature-based molecular networking for metabolite identification.

Main Results:

Specialized metabolites

Wild edible plants

Annotation of 347 primary and specialized metabolites across 8 biochemical classes.
Polyphenols and anthraquinones constituted the majority (60%) of identified metabolites.
Quantification of emodin revealed higher accumulation in leaves compared to stems and roots.

Conclusions:

Metabolomic studies are crucial for understanding both beneficial and potentially harmful compounds in medicinal plants transitioning to culinary use.
The presence and distribution of specific metabolites like emodin warrant consideration for safe consumption.