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At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
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Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
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Related Experiment Video

Updated: May 31, 2025

Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients
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The relationship between vitamin A and myopia: A population-based study.

Yeo Jin Lee1,2, Donghyun Jee1,3

  • 1Department of Ophthalmology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Plos One
|January 24, 2025
PubMed
Summary

Higher blood vitamin A levels are linked to a reduced prevalence of myopia in adults. This study found that increased vitamin A intake may be protective against myopia development, especially in women and men with high myopia.

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Area of Science:

  • Ophthalmology
  • Nutrition Science
  • Public Health

Background:

  • Myopia, or nearsightedness, is a growing global health concern.
  • Vitamin A plays a crucial role in vision and cellular processes.
  • Understanding nutritional factors influencing myopia is vital for prevention strategies.

Purpose of the Study:

  • To investigate the association between blood vitamin A levels and myopia prevalence in Korean adults (≥20 years).
  • To explore potential gender-specific relationships between vitamin A and myopia or high myopia.

Main Methods:

  • Analysis of data from 15,899 participants in the Korean National Health and Nutrition Examination Survey.
  • Assessment of myopia and high myopia through refraction tests.
  • Measurement of blood vitamin A levels, categorized into quartiles, alongside other health indicators.

Main Results:

  • Adjusted analyses revealed an inverse relationship between higher blood vitamin A levels and myopia prevalence (P for trend < 0.001).
  • In women, elevated vitamin A levels were associated with lower odds of myopia (2nd quartile OR: 0.48, 3rd quartile OR: 0.67).
  • In men, higher vitamin A levels significantly reduced the odds of high myopia (2nd, 3rd, and 4th quartiles showed ORs of 0.05, 0.15, and 0.05, respectively).

Conclusions:

  • Higher blood vitamin A levels are inversely correlated with myopia prevalence in Korean adults.
  • Vitamin A sufficiency may offer a protective effect against myopia, particularly high myopia in men and myopia in women.
  • Further research into vitamin A supplementation for myopia prevention is warranted.