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Related Concept Videos

Lewis Acids and Bases02:33

Lewis Acids and Bases

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In 1923, G. N. Lewis proposed a generalized definition of acid-base behavior in which acids and bases are identified by their ability to accept or to donate a pair of electrons and form a coordinate covalent bond.
A coordinate covalent bond (or dative bond) occurs when one of the atoms in the bond provides both bonding electrons. For example, a coordinate covalent bond occurs when a water molecule combines with a hydrogen ion to form a hydronium ion. A coordinate covalent bond also results when...
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Metal-Ligand Bonds02:51

Metal-Ligand Bonds

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The hemoglobin in the blood, the chlorophyll in green plants, vitamin B-12, and the catalyst used in the manufacture of polyethylene all contain coordination compounds. Ions of the metals, especially the transition metals, are likely to form complexes.
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
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Formation of Complex Ions03:45

Formation of Complex Ions

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A type of Lewis acid-base chemistry involves the formation of a complex ion (or a coordination complex) comprising a central atom, typically a transition metal cation, surrounded by ions or molecules called ligands. These ligands can be neutral molecules like H2O or NH3, or ions such as CN− or OH−. Often, the ligands act as Lewis bases, donating a pair of electrons to the central atom. These types of Lewis acid-base reactions are examples of a broad subdiscipline called coordination...
23.2K
[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction01:16

[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction

10.0K
The Diels–Alder reaction is an example of a thermal pericyclic reaction between a conjugated diene and an alkene or alkyne, commonly referred to as a dienophile. The reaction involves a concerted movement of six π electrons, four from the diene and two from the dienophile, forming an unsaturated six-membered ring. As a result, these reactions are classified as [4+2] cycloadditions.
10.0K
Properties of Organometallic Compounds01:23

Properties of Organometallic Compounds

931
Organometallic compounds are compounds that contain a carbon–metal bond. Carbon belongs to an organyl group like alkyl, aryl, allyl, or benzyl groups. The metal can be from Group I or Group II of the periodic table, a transition metal, or a semimetal.
931
Electrophilic 1,2- and 1,4-Addition of X2 to 1,3-Butadiene01:14

Electrophilic 1,2- and 1,4-Addition of X2 to 1,3-Butadiene

2.3K
Electrophilic addition of halogens to alkenes proceeds via a cyclic halonium ion to form a 1,2-dihalide or a vicinal dihalide.
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Related Experiment Video

Updated: May 31, 2025

Characterizing Lewis Pairs Using Titration Coupled with In Situ Infrared Spectroscopy
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Characterizing Lewis Pairs Using Titration Coupled with In Situ Infrared Spectroscopy

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Lewis Base-Enhanced C-H Bond Functionalization Mediated by a Diiron Imido Complex.

Reilly K Gwinn1, Trevor P Latendresse2, Owen N Beck1

  • 1Department of Chemistry, Virginia Tech, Blacksburg, Virginia 24061, United States.

Inorganic Chemistry
|January 24, 2025
PubMed
Summary

Ligand design enables exclusive bimetallic pathways for C-H functionalization using diiron imido complexes. These complexes facilitate hydrogen atom abstraction and Lewis base-enhanced reactions, proving bimetallic intermediates are key.

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Imine Metathesis by Silica-Supported Catalysts Using the Methodology of Surface Organometallic Chemistry

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Imine Metathesis by Silica-Supported Catalysts Using the Methodology of Surface Organometallic Chemistry
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Area of Science:

  • Organometallic Chemistry
  • Catalysis
  • Synthetic Chemistry

Background:

  • Metal-ligand multiply bonded (MLMB) complexes offer unique reactivity.
  • Controlling nuclearity is crucial for selective catalytic pathways.
  • C-H bond functionalization remains a significant challenge in synthetic chemistry.

Purpose of the Study:

  • To investigate how ligand design influences the nuclearity and reactivity of diiron complexes.
  • To develop an exclusively bimetallic reaction pathway for C-H bond functionalization.
  • To explore the catalytic potential of diiron imido complexes in C-H activation.

Main Methods:

  • Synthesis of diiron alkoxide, imido, and amide complexes.
  • Treatment of diiron alkoxide with an azide to form imido species.
  • Isolation and characterization of various diiron complexes.
  • Catalytic testing for C-H bond functionalization reactions, including toluene amination.

Main Results:

  • A diiron imido complex capable of hydrogen atom abstraction (HAA) was synthesized.
  • Various diiron complexes with bridging amide and terminal alkoxide ligands were isolated.
  • An asymmetric pyridine-bound diiron imido complex showed competence in toluene amination.
  • Mechanistic studies indicated that bimetallic bridging imido complexes are the active intermediates.

Conclusions:

  • Ligand design can control the nuclearity and reactivity of MLMB complexes.
  • Diiron imido complexes provide a viable platform for bimetallic C-H functionalization.
  • Lewis base coordination enhances C-H functionalization efficiency in these systems.