Related Experiment Video
Updated: May 31, 2025
05:54
Stereo-Electro-Encephalo-Graphy SEEG With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
Published on: June 13, 2016
17.1K
Enhancing epilepsy care in Argentina: Use of SEEG in a developing setting
Silvia Oddo1, Brenda Giagante1, Eduardo Seoane1
1Neuroscience Service, High Complexity El Cruce, "Nestor Kirchner" Hospital, ENYS. UNAJ. CONICET, Florencio Varela, Provincia de Buenos Aires, Argentina.
Neurophysiologie Clinique = Clinical Neurophysiology
|January 24, 2025
Summary
Stereoelectroencephalography (SEEG) in drug-resistant epilepsy patients in Argentina demonstrated successful presurgical evaluation. This advanced epilepsy care is achievable in developing regions with proper training and resources.
Area of Science:
- Neurology
- Neurosurgery
- Epileptology
Background:
- Drug-resistant epilepsy (DRE) poses significant challenges in patient management.
- Epilepsy presurgical evaluation is crucial for identifying candidates for surgical intervention.
- Stereoelectroencephalography (SEEG) is an advanced invasive neuroimaging technique for precise localization of the epileptogenic zone.
Purpose of the Study:
- To describe the characteristics and outcomes of DRE patients undergoing SEEG for presurgical evaluation.
- To assess the feasibility and effectiveness of SEEG in a high-complexity public hospital in Argentina.
- To evaluate the surgical treatment indications and post-surgical outcomes in this population.
Main Methods:
- Retrospective study of 49 DRE patients from 2014-2023 who underwent SEEG.
- Analysis of MRI findings, epileptogenic zone (EZ) location, surgical procedures, neuropsychological evaluations, and histopathology.
- Evaluation of post-surgical outcomes using the International League Against Epilepsy (ILAE) classification.
Main Results:
- 43% of patients had normal MRI findings.
- Surgical treatment was indicated in 61.2% of patients.
- Post-surgery outcomes were ILAE I (26.6%) and ILAE II (30%).
Conclusions:
- High-quality epilepsy care, including SEEG, is achievable in Argentina.
- Proper training and resource allocation are key to successful implementation of advanced epilepsy procedures.
- This experience suggests SEEG is feasible in other developing regions.
Related Concept Videos
01:30Electroconvulsive Therapy
22
Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
22
01:24Arteries of the Lower Limbs
177
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
177
01:18Antiepileptic Drugs: GABAergic Pathway Potentiators
316
γ-aminobutyric acid or GABA, plays a pivotal role as an inhibitory neurotransmitter in the brain. GABA pathway potentiators, also known as GABAergic drugs, are a class of pharmaceutical agents designed to enhance the functioning of the GABAergic system. These medications primarily treat epilepsy, a neurological disorder characterized by recurrent seizures.
The key GABA pathway potentiators used in epilepsy management are as follows.
Benzodiazepines are a well-known class of drugs used for...
The key GABA pathway potentiators used in epilepsy management are as follows.
Benzodiazepines are a well-known class of drugs used for...
316
01:14Antiepileptic Drugs: Glutamate Antagonists
273
Glutamate is a fundamental neurotransmitter in the central nervous system, playing a vital role in neuronal communication and various cognitive processes. Glutamate stands as the principal excitatory neurotransmitter in the brain. Its presence is crucial for the communication between neurons, underpinning essential processes such as synaptic transmission, neuronal excitability, and plasticity. These functions are vital for higher-order cognitive processes, including learning and memory. The...
273
01:08Antiepileptic Drugs: Sodium Channel Blockers
367
Antiepileptic drugs are specialized medications that prevent seizures in individuals diagnosed with epilepsy. These drugs primarily function by blocking the movement of sodium ions through channels in the neuronal membrane, inhibiting the repetitive firing of action potentials often associated with seizures.
Sodium channel blockers modulate ion channels, particularly voltage-gated sodium channels. They block only sodium ion movement.
Among the most commonly prescribed antiepileptic drugs are...
Sodium channel blockers modulate ion channels, particularly voltage-gated sodium channels. They block only sodium ion movement.
Among the most commonly prescribed antiepileptic drugs are...
367