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Updated: May 31, 2025

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
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A promising advance using oncolytic adenovirus to locally block tumorigenic TNF signaling

Yalei Zhang1, Peng Wang2

  • 1Department of Hepatic Oncology, Zhongshan Hospital, Fudan University, Shanghai, China; Liver Cancer Institute, Zhongshan Hospital, Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Fudan University, Shanghai, China; Department of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.

Molecular Therapy : the Journal of the American Society of Gene Therapy
|January 24, 2025
PubMed
Abstract

No abstract available in PubMed .

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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