Related Experiment Video
Updated: May 31, 2025
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Endovascular Therapy is Effective in Patients with Post-Thrombotic Syndrome Based on Anatomical Classification: A
Yulong Huang1, Xinsheng Xie1, Xiaolin Yu2
1Department of Vascular Surgery, Xiamen Branch of Zhongshan Hospital, Fudan University, Xiamen, China.
Insights
This study shows endovascular therapy is safe and effective for post-thrombotic syndrome (PTS), offering good long-term outcomes. A new classification system may guide treatment strategies for PTS patients.
Area of Science:
- Vascular Surgery
- Interventional Radiology
Background:
- Post-thrombotic syndrome (PTS) significantly impacts patient quality of life.
- Long-term outcomes and effective treatment strategies for PTS require further investigation.
Purpose of the Study:
- To retrospectively review long-term outcomes of patients with post-thrombotic syndrome (PTS).
- To investigate the efficacy and safety of endovascular therapy for PTS.
- To present a novel classification system for PTS to guide treatment.
Main Methods:
- Retrospective evaluation of 83 patients (86 limbs) with PTS undergoing endovascular therapy across two institutions (Jan 2018 - Sep 2023).
- Classification of lesions based on inflow sufficiency (digital subtraction angiography - DSA).
- Collection and analysis of baseline demographics, lesion characteristics, and in-hospital/follow-up outcomes.
Main Results:
- Successful endovascular treatment in 89.53% of limbs (77/86).
- 46 limbs received angioplasty with stenting; 31 received angioplasty alone, primarily for insufficient inflow.
- Mean follow-up was 23.44 months; low complication rates (in-stent restenosis, occlusive endograft edge) observed in stent cohort.
Conclusions:
- Endovascular therapy demonstrates safety and effectiveness for PTS treatment.
- Promising long-term prognosis observed with endovascular interventions for PTS.
- The proposed novel PTS classification may aid in endovascular treatment strategy planning.
Background:
In this study, we aimed to retrospectively review patients with post-thrombotic syndrome (PTS) and investigate its long-term outcomes, and a novel classification were presented across multiple institutions.
Methods:
We retrospectively evaluated patients with PTS who underwent endovascular therapy at 2 institutions between January 2018 and September 2023. Baseline patient demographics, lesion characteristics, and in-hospital and follow-up outcomes were collected and analyzed retrospectively.
Results:
83 patients (86 limbs) patients suffered PTS received endovascular related surgery at the 2 institutions. The lesions were summarized into 2 categories: sufficient or insufficient inflow according to digital subtraction angiography (DSA). 77 limbs (89.53%) underwent successful endovascular treatment including 46 limbs receiving percutaneous transluminal angioplasty (PTA) and stent implantation, and 31 limbs undergoing PTA without stent deployment was mainly contributed to insufficient inflow. The mean follow-up time was 23.44 ± 16.91 months (range, 6-60 months) in stent implantation cohort. In-stent restenosis and an occlusive endograft edge were observed in 2 cases, respectively. No other stent-related complications, such as fractures or migration, were noted in any patient during the follow-up period.
Conclusions:
Endovascular technique was safe and effective for the treatment of PTS and showed promising long-term prognosis. The novel classification of PTS might be feasible for the strategy of endovascular treatment.
