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Histoplasmosis in a Solid Organ Transplant Patient in a Non-Endemic Region in New York City
Sarah Shidid1, Aashna Pandya2, Kateryna Karpoff2
1Department of Medicine, Division of General Internal Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA sarah.shidid@gmail.com.
Objective:
To present the case of a solid organ transplant recipient with Histoplasmosis in New York City.
Case Report:
We present a 39-year-old female liver transplant recipient, who experienced a two-week history of progressive shortness of breath and dyspnea on exertion that interfered with all activities of daily living. Physical examination by the team revealed the patient had a WBC of 11.7, + SARS-CoV-2 NP swab, CT Chest with pneumonia, and a urine antigen test positive for Histoplasmosis. Her overall clinical picture was concerning for new Histoplasmosis infection.
Conclusion:
Findings endorse the diagnosis of Histoplasmosis. Histoplasmosis is rare in non-endemic regions such as New York City. An infectious workup should include fungal markers to further evaluate shortness of breath and a need to look beyond epidemiologic measures.
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