Patient-reported outcomes in sarcopenia: An ICFSR task force report

Area of Science:

• Gerontology
• Clinical Medicine
• Rehabilitation Science

Background:

• Patient-reported outcome measures (PROMs) are essential for evaluating healthcare quality and patient experience.
• Sarcopenia research increasingly recognizes the value of PROMs to complement objective measures.
• Pharmaceutical industries and regulatory bodies are emphasizing PROMs in clinical trial design.

Purpose of the Study:

• To present validated patient-reported outcome measures (PROMs) for sarcopenia.
• To highlight the current state-of-the-art PROMs applicable in clinical settings.
• To identify research gaps and barriers hindering PROM utilization in sarcopenia clinical trials.

Main Methods:

• A comprehensive review of existing literature on PROMs for sarcopenia.
• Analysis of validated PROMs suitable for clinical application and research.
• Identification of key challenges and future research directions.

Main Results:

• Several validated PROMs for sarcopenia are available for clinical and research use.
• There is a growing recognition of PROMs' importance in sarcopenia assessment.
• Significant research gaps and implementation barriers persist.

Conclusions:

• Validated PROMs are critical tools for advancing sarcopenia research and patient care.
• Addressing identified research gaps is necessary to optimize PROM integration into clinical trials.
• Further development and validation efforts are needed to enhance the utility of PROMs in sarcopenia.