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Depression Detection and Diagnosis Based on Electroencephalogram (EEG) Analysis: A Systematic Review
Kholoud Elnaggar1, Mostafa M El-Gayar1,2, Mohammed Elmogy1
1Information Technology Department, Faculty of Computers and Information, Mansoura University, Mansoura 35516, Egypt.
Diagnostics (Basel, Switzerland)
|January 25, 2025
Summary
Electroencephalogram (EEG) data combined with artificial intelligence (AI) shows promise for diagnosing depression. This review highlights AI-driven methods using EEG for improved mental health diagnosis and future research directions.
Area of Science:
- Neuroscience
- Computer Science
- Psychiatry
Background:
- Mental disorders, including depression, significantly impact global public health and suicide rates.
- Electroencephalogram (EEG) data offers insights into brain function, aiding in the diagnosis of mild depression disorder (MDD).
Purpose of the Study:
- To survey artificial intelligence (AI)-driven approaches for depression diagnosis using Electroencephalogram (EEG) data.
- To analyze methods integrating EEG with machine learning (ML) and deep learning (DL) for identifying depression biomarkers.
Main Methods:
- Systematic analysis of studies employing EEG signals with ML and DL techniques.
- Review of EEG preprocessing, feature extraction, and model development for depression detection.
- Comparison of ML and DL approaches and analysis of existing depression diagnosis datasets.
Main Results:
- AI-driven EEG analysis enhances diagnostic precision, scalability, and automation for depression detection.
- Identified limitations in current datasets and proposed data augmentation and channel selection for improved accuracy.
- Explored future directions including transfer learning, IoT integration for continuous monitoring, and distinguishing depression subtypes.
Conclusions:
- This review serves as a reference for researchers in EEG-based depression detection.
- Provides insights into future research directions for advancing AI-driven mental health diagnostics.

