Comparative cytomorphometric and cytospectrophotometric investigations of gastric lesions

Comparative cytomorphometric and cytospectrophotometric investigations have been carried out on Hematoxylin-Eosin and Feulgen stained paraffin sections from 150 patients with normal gastric mucosa, chronic atrophic and hypertrophic gastritis, benign and malignantly transformed stomach ulcers and adenomatous polyps and adenocarcinoma of the stomach. The changes in the small and large nucleus (cell) diameters; nucleus, cell and cytoplasma area (volume) and nucleus/cell and nucleus/cytoplasma ratio for area and volume as well as the nuclear DNA content values have been presented in the pathway from normal stomach mucosa to gastric cancer. The presented results give us more information about the dynamics of malignant cell transformation.