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Updated: May 31, 2025

Development and Assessment of Intracellular Infection Models for Staphylococcus aureus
Published on: January 17, 2025
Strategies for Survival of Staphylococcus aureus in Host Cells
Huiling Xu1, Shengnan Wang1, Xiaoting Liu1
1College of Veterinary Medicine, Shandong Agricultural University, Tai'an 271018, China.
Abstract:
Staphylococcus aureus, a common pathogen, is capable of producing a significant array of toxins and can develop biofilms or small colony variants (SCVs) to evade detection by the immune system and resist the effects of antibiotics. Its ability to persist for extended periods within host cells has led to increased research interest. This review examines the process of internalization of S. aureus, highlighting the impact of its toxins and adhesion factors on host cells. It elucidates the intricate interactions between them and the host cellular environment, thereby offering potential strategies for the treatment and prevention of S. aureus infections.
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