Monoamine oxidase in single nerve cell bodies from locus coeruleus of the rat. A microgasometric study

The magnetic diver microgasometer was used for determination of MAO activity in single nerve cell bodies isolated from the locus coeruleus of the rat. Tyramine was used as a substrate. Both molecular forms of MAO, MAO A and MAO B, are present in single nerve cell as shown by clorgyline, a selective inhibitor of MAO A molecular form. The activity of MAO in nerve cell bodies from locus coeruleus was compared to the activities in seven other types of nerve cells.