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Related Experiment Video

Updated: May 30, 2025

Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy

Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy

Published on: May 27, 2020

The Brain's Aging Resting State Functional Connectivity.

Ali F Khan¹, Nada Saleh², Zachary A Smith¹

¹Department of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.

Journal of Integrative Neuroscience

|January 25, 2025

Summary

This summary is machine-generated.

Brain

Keywords:

aging cortical reserve fMRI functional connectivity neuroplasticity resting state networks

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Last Updated: May 30, 2025

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Acquisition of Resting-State Functional Magnetic Resonance Imaging Data in the Rat

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Published on: August 28, 2021

Area of Science:

Neuroscience
Brain Aging Research
Functional Neuroimaging

Background:

Resting state networks (RSNs) reflect spontaneous brain activity.
RSNs are crucial for understanding brain organization in health and disease.
Aging significantly alters RSNs' spatiotemporal properties.

Purpose of the Study:

To review functional magnetic resonance imaging (fMRI) findings on age-related RSN changes.
To discuss mechanisms underlying these alterations.
To identify methodological challenges and future research directions.

Main Methods:

This is a narrative review.
Focuses on studies utilizing functional magnetic resonance imaging (fMRI).
Synthesizes existing literature on aging and RSNs.

Main Results:

Aging impacts the spatiotemporal dynamics of RSNs.
Neural plasticity in RSNs may compensate for cognitive decline.
Specific age-related alterations in RSNs are observed.

Conclusions:

Understanding age-related RSN changes is vital for brain health.
This review guides research toward promoting healthy aging.
Insights can inform interventions for cognitive impairment and neurodegeneration.