[Morphogenesis of inflammation of the lungs with changed immunity]

Two-week pneumonia was induced in Wistar rats by introduction of a foreign body into the trachea under the effect of heparin, cyclophosphamide, phytohemagglutinin, and liquid paraffin. The morphological and immunological features of the processes were studied. It was discovered that modification of the inflammatory process provoked by the use of the above-mentioned substances is not connected with their immunoregulatory effects or with the induced changes in the humoral and cellular immune response. The data obtained are regarded as evidence for the possibility of the absence of the relationship between the development of the inflammatory process and the status of immunity.