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Related Experiment Videos

[Hyperprolactinemic hypogonadism--pathogenesis, diagnosis and therapy].

F E Ulrich

    Zeitschrift Fur Die Gesamte Innere Medizin Und Ihre Grenzgebiete
    |October 15, 1979
    PubMed
    Summary

    Elevated prolactin levels disrupt reproductive health in both women and men. New therapies targeting the hypothalamus-pituitary axis offer hope for fertility issues caused by hyperprolactinemia.

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    [Ontogenetic changes in the circadian rhythm of plasma insulin and its correlation to food intake].

    Biomedica biochimica acta·1987

    Area of Science:

    • Endocrinology
    • Reproductive Medicine

    Background:

    • Hyperprolactinemia affects approximately 30% of women with amenorrhea.
    • Pituitary or hypothalamic tumors account for 10% of these cases.
    • Hyperprolactinemia can cause galactorrhea, amenorrhea, and male impotence.

    Purpose of the Study:

    • To investigate the role of prolactin in hypogonadism.
    • To explore new therapeutic strategies for fertility disturbances.
    • To highlight the importance of prolactin assessment in reproductive health.

    Main Methods:

    • Review of existing literature on prolactin and fertility.
    • Discussion of dopaminergic agents in managing hyperprolactinemia.
    • Consideration of WHO recommendations for prolactin testing.

    Main Results:

    • Dopaminergic substances can inhibit prolactin secretion, offering conservative treatment for fertility issues.
    • Physiological effects of prolactin adequately explain hypogonadism development.
    • Radioimmunologic determination of prolactin is crucial for diagnosing hypogonadism.

    Conclusions:

    • Hyperprolactinemia is a significant factor in reproductive dysfunction.
    • Dopaminergic therapy presents a viable option for treating fertility disturbances.
    • Management of hyperprolactinemic infertility requires multidisciplinary collaboration.

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