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Updated: Jul 6, 2026

Cell Lineage Analyses and Gene Function Studies Using Twin-spot MARCM

Cell Lineage Analyses and Gene Function Studies Using Twin-spot MARCM

Published on: March 2, 2017

Krait2: a versatile software for microsatellite investigation, visualization and marker development.

Lianming Du¹, Jiahao Chen², Dalin Sun²

¹Antibiotics Research and Re-Evaluation Key Laboratory of Sichuan Province, School of Pharmacy, Chengdu University, Chengdu, 610106, China. dulianming@cdu.edu.cn.

|January 25, 2025

Summary

Krait2 is a new, user-friendly software tool for analyzing microsatellites in genomic data. It offers advanced features for identifying and studying these important genetic markers across multiple genomes.

Keywords:

Genetic marker Genomes Microsatellite Primer design Tandem repeats

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Area of Science:

Genomics
Bioinformatics

Background:

Microsatellites are polymorphic repeat sequences crucial for molecular marking.
Microsatellite expansions are linked to gene regulation, neurological diseases, and cancers.
Existing tools lack comprehensive large-scale microsatellite analysis capabilities.

Purpose of the Study:

To introduce Krait2, a powerful and user-friendly tool for microsatellite analysis.
To provide a solution for large-scale investigation of microsatellites in genomic datasets.

Main Methods:

Developed Krait2, a graphical software tool.
Integrated features for identifying perfect, imperfect, and compound microsatellites.
Enabled analysis of FASTA and FASTQ formatted genomic data.

Main Results:

Krait2 supports primer design, repeat filtering, annotation, and statistical analysis.
The tool offers customizable output formats for downstream analysis.
Krait2 facilitates simultaneous analysis of multiple genomes and comparative studies.

Conclusions:

Krait2 is a versatile and accessible software for microsatellite identification and analysis.
The software is suitable for both novice and expert users.
Krait2 is available with source code and installer for broader accessibility.