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Individualized total knee arthroplasty achieves better functional results than off-the-shelf implants in patients
Bernard de Geofroy1, Tristan Fauchille2, Michael Djian3
1Department of Orthopaedic and Trauma Surgery, HIA Laveran, Marseille, France.
Background:
Several studies have demonstrated the interest in patient-specific custom cutting guides in total knee arthroplasty (TKA), but clinical improvement remains debated. The purpose of this study was to evaluate the functional outcomes (Forgotten Joint Score, FJS) of patients undergoing individualized TKA compared with those receiving off-the-shelf (OTS) implants, both using patient-specific cutting guides with personalized alignment over a minimum follow up period of 12 months. We hypothesized that individualized TKA demonstrates significantly better functional outcomes than OTS TKA (FJS and percentage of patients reaching the minimum clinically important difference).
Methods:
A continuous single-surgeon retrospective series was analyzed from September 2018 to June 2020. The inclusion criterion was primary TKA for osteoarthritis. The series compared 58 individualized TKAs to 54 standard implants, with personalized alignment, at a mean follow up of 25 (12-40) months. The two groups were comparable in gender, age, BMI, and preoperative deformity. Complications and revision procedures were recorded. The FJS, New IKS, and Oxford Knee Score were assessed at the last follow up, and the sensation of a forgotten knee was evaluated.
Results:
One patient in each group required TKA revision. At last follow up, the individualized TKA group showed significantly better FJS (91 ± 14 vs. 81 ± 23, P = 0.01), satisfaction category in the IKS (36 ± 5 vs. 32 ± 8, P = 0.002), IKS function (83 ± 11 vs. 72 ± 21, P = 0.003) and Oxford scores (44 ± 5 vs. 39 ± 10, P = 0.005. There was no significant difference in the IKS objective score (88 ± 16 vs. 82 ± 2, P = 0.34). The sensation of a forgotten knee rate did not differ significantly between the groups.
Conclusion:
Individualized TKA leads to improved clinical outcomes significantly compared with OTS TKA, utilizing personalized alignment and patient-specific cutting guides. This combination of personalized factors and individualized TKA enhances the potential to tackle the challenges associated with TKA and improve functional results.
