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[Investigation of the Influence of Image Reconstruction Parameters to Improve the Ability to Depict Internal Tumor
Yuka Sakamoto1, Yoshihiro Yamamoto1, Tadaaki Uegaki1
1Department of Radiology, Nara Prefecture General Medical Center.
Purpose:
There are attempts to assess tumor heterogeneity by texture analysis. However, the ordered subsets-expectation maximization (OSEM) reconstruction method has problems depicting heterogeneities. The aim of this study was to identify image reconstruction parameters that improve the ability to depict internal tumor necrosis using a self-made phantom that simulates internal necrosis.
Methods:
Self-made phantoms were prepared using polypropylene cylinders with inner diameters of 18.0 mm and 6.0 mm. The concentration ratios of the simulated tumor : tumor interior were 4 : 0 and 4 : 1. For each reconstruction method, the iteration for OSEM and OSEM+point spread function (PSF) were 1 to 25 and the subset was 12. The β values for block sequential regularized expectation maximization (BSREM) were set between 10 and 400. We evaluated the features of the profile curve, contrast-to-noise ratio, and grey-level co-occurrence matrix (GLCM).
Results:
In the phantom study, OSEM and OSEM+PSF showed a better delineation of the differences between the inside and outside of the cylinder as iteration was increased and BSREM showed a better delineation as β was decreased. The highest value for each feature, both 4 : 0 and 4 : 1, was BSREM β 10 for angular second moment (ASM) and inverse differential moment (IDM), OSEM iteration 25 for contrast and entropy.
Conclusion:
We have identified image reconstruction parameters that improve the ability to visualize internal tumor necrosis. The parameter was BRSEM β 10.
