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Identification of Novel HLA-DQA1 and -DQB1 Alleles: DQA1*05:118 and DQB1*03:01:01:73

J Gonzalo Ocejo-Vinyals1, Nerea Mota-Pérez1, Mónica Renuncio García1

  • 1Servicio de Inmunología, Laboratorio de Histocompatibilidad, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain.

HLA
|January 26, 2025
PubMed

Abstract:

Description of the novel HLA-DQA1*05:118 and -DQB1*03:01:01:73 alleles.

Keywords:
DQA1*05:118DQB1*03:01:01:73HLA novel allelesHLA‐DQ

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Blood Types02:20

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Human blood is classified into different types based on the presence of antigens on the red blood cell's surface and antibodies in the plasma. Proper identification of blood type is essential for successful blood transfusion. The International Society of Blood Transfusion has identified 38 human blood types based on the surface antigens on the red blood cells. The most common types are ABO, Rh, and MNS blood types.
ABO blood group
ABO antigens are glycoproteins encoded by genes present on...
Blood Typing01:10

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Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target antigens A,...

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