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Identification of the Novel HLA-C*06:44:02 Allele by Next-Generation Sequencing in a Serbian Individual

Barbara Jovanovic1, Zorana Andric1, Danica Velickovic1

  • 1Blood Transfusion Institute of Serbia, Belgrade, Serbia.

HLA
|January 26, 2025
PubMed

Keywords:
HLA‐C*06:44:02Illuminanew allelenext‐generation sequencing

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...