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Deciphering the Topology of Sitagliptin Using an Integrated Approach

Renny Mathew1, Brijith Thomas1

  • 1Science Division, New York University Abu Dhabi, P.O. Box 129188, Abu Dhabi, United Arab Emirates.

ACS Omega
|January 27, 2025
PubMed
Summary

This study precisely determined the structure of sitagliptin, a DPP-4 inhibitor for type 2 diabetes, using advanced NMR and electron diffraction. This ensures drug effectiveness and quality control in pharmaceutical manufacturing.

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