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Neurocognitive Markers during Maximum Alcohol Use in Late Adolescence as Predictors of Change in Later Drinking
Nafisa Ferdous1, María Luisa Zúñiga2, Kelly E Courtney3
1JDP in Interdisciplinary Research on Substance Use, Division of Global Public Health, UC San Diego, and School of Social Work, San Diego State University, San Diego, CA, USA.
Background:
The influence of alcohol use on later neurocognitive functioning is well researched, yet few studies have investigated whether neurocognition post-drinking initiation in adolescence predicts changes in later alcohol use.
Objective:
Investigate neurocognitive task performance during maximum alcohol use in late adolescence as predictors of drinking behaviors 3-7 years later.
Methods:
Analyses (n=105) were conducted on a longitudinal dataset involving adolescents (12-13 years-old) who were followed for 16 years. Time 1 (T1) was defined as the individuals' maximum drinking year within the first 10 study years and Time 2 (T2) was the first available data entry 3-7 years after T1. Four hierarchical linear regression models predicting follow-up alcohol use were estimated: drinking days, average drinks per drinking day, peak drinks, and binge episodes. All models included inhibition/cognitive flexibility, visuospatial ability, verbal memory, working memory, and their interactions with sex, while covarying for age at T1, follow-up duration and controlling for T1 drinking.
Results:
Better visuospatial ability at T1 predicted decreases in later binge episodes at T2 (β= -.19, p= .048, partial r2 = .039). While better inhibition/cognitive flexibility at T1 predicted increases in follow-up drinks per drinking day at T2 (β= .18, p= .016, partial r2= .057).
Conclusion:
Findings suggest specific neurocognitive abilities during maximum drinking in late adolescence are useful as predictors of change in later drinking quantity per occasion and could potentially inform intervention research targeting this age group.
