Related Experiment Video
Updated: May 30, 2025

A Murine Model of Vertical Sleeve Gastrectomy
Published on: December 18, 2017
Health Expenditures of Patients With Diabetes After Bariatric Surgery: Comparing Gastric Bypass and Sleeve
Matthew L Maciejewski1, Lindsay Zepel2, Valerie A Smith3
1Center of Innovation to Accelerate Discovery and Practice Transformation, Durham VA Medical Center; Department of Population Health Sciences, Duke University; and Division of General Internal Medicine, Department of Medicine, Duke University, Durham, North Carolina (M.L.M.).
Background:
Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) differ in their effects on body weight and risk for reoperation. However, it is unclear whether long-term health expenditures differ by procedure type in patients with diabetes.
Objective:
To compare health expenditures 3 years before and 5.5 years after bariatric surgery between patients with diabetes undergoing RYGB versus SG.
Design:
Retrospective cohort study using target trial emulation principles.
Setting:
Integrated health system.
Patients:
Patients with diabetes undergoing RYGB (n = 3147) or SG (n = 3510) from 2012 to 2019.
Measurements:
Total, inpatient, outpatient, and medication expenditures.
Results:
Characteristics of patients undergoing RYGB and SG were well balanced after weighting; 73% were female, average body mass index was 43.8 kg/m2, and average age was 50 years. Expenditures per 6-month period decreased by about 30% for both groups, from $4039.06 (95% CI, $3770.88 to $4326.31) 3 years before to $2441.13 (CI, $2151.07 to $2770.30) 5.5 years after RYGB and from $3918.37 (CI, $3658.75 to $4196.40) 3 years before to $2658.15 (CI, $2279.17 to $3100.16) 5.5 years after SG. Total expenditures after surgery did not differ between groups through 5.5 years (difference at 5.5 years, -$217.02 [CI, -$671.29 to $201.96]) except for the first 6 months, when expenditures were transiently higher in the RYGB group (difference, $564.32 [CI, $232.60 to $895.20]), driven by a higher inpatient admission rate. Otherwise, postsurgical outpatient and medication expenditures did not appear to differ between RYGB and SG.
Limitation:
Unobserved confounding.
Conclusion:
Overall expenditures decreased substantially in the postsurgical period, primarily due to reductions in pharmacy expenditures, with no differences between RYGB and SG except in the first 6 months after surgery.
Primary Funding Source:
National Institute of Diabetes and Digestive and Kidney Diseases.
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