Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of mental health on outcomes of patients with relapsed and/or refractory diffuse large B-cell lymphoma treated with chimeric antigen receptor T-cell therapy.

Hematology/oncology and stem cell therapy·2026
Same author

A Harmonized International Database of More Than 10,000 Pediatric Renal Tumor Patients From 30 Years of SIOP-RTSG Studies.

JCO clinical cancer informatics·2026
Same author

Diagnostic Utility and Clinical Implications of Inpatient Fecal Occult Blood Testing.

Southern medical journal·2026
Same author

Unusual presentation of Currarino syndrome in an infant with right gluteal abscess.

BMJ case reports·2026
Same author

Intraoperative Stenting of Hepatic Ducts to Aid Dissection in an 8-Month-Old Child with Large Hepatoblastoma and Severe Porta Distortion.

Indian journal of surgical oncology·2026
Same author

Efficacy of bispecific T-cell engagers after CAR T-cell therapy failure in aggressive large B-cell lymphoma.

Current research in translational medicine·2026

Related Experiment Video

Updated: Jun 14, 2026

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma
09:25

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma

Published on: October 14, 2016

19.1K

Evidence-Based Surgical Guidelines for Treating Children With Rhabdomyosarcoma.

Abdelhafeez H Abdelhafeez1,2,3, Tea Reljic4, Farina Klocksieben4

  • 1Department of Surgery, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

Pediatric Blood & Cancer
|January 27, 2025
PubMed
Summary

New clinical practice guidelines offer standardized surgical approaches for pediatric rhabdomyosarcoma (RMS). Key recommendations include lymph node evaluation and specific margin guidelines for improved treatment outcomes in children with RMS.

Keywords:
RMSguidelinesrhabdomyosarcomasurgery

More Related Videos

Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas
09:21

Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas

Published on: September 13, 2019

7.1K
Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model
13:41

Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model

Published on: January 13, 2023

2.3K

Related Experiment Videos

Last Updated: Jun 14, 2026

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma
09:25

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma

Published on: October 14, 2016

19.1K
Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas
09:21

Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas

Published on: September 13, 2019

7.1K
Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model
13:41

Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model

Published on: January 13, 2023

2.3K

Area of Science:

  • Pediatric Oncology
  • Surgical Oncology
  • Clinical Practice Guidelines

Background:

  • Surgery is the primary treatment for pediatric rhabdomyosarcoma (RMS).
  • Global variations in surgical management necessitate standardized Clinical Practice Guidelines (CPG).

Purpose of the Study:

  • To develop evidence-based CPG for surgical management of pediatric RMS.
  • To address variations in surgical practices worldwide.

Main Methods:

  • Assembled a multidisciplinary expert panel.
  • Conducted systematic evidence searches and synthesized findings.
  • Utilized the GRADE methodology for formulating recommendations.

Main Results:

  • Recommended regional lymph node evaluation for specific pediatric RMS subtypes (paratesticular >10 years, extremity).
  • Suggested pretreatment re-excision for incomplete resections and preoperative radiation for unresectable tumors.
  • Advocated for a 0.5 cm resection margin, tumor bed marking, and resection of residual/relapsed disease.

Conclusions:

  • These CPG offer standardized, evidence-based surgical management strategies for pediatric RMS.
  • Recommendations are adaptable to various resource settings globally.