Frequency of alkaline phosphatase-immunoglobulin complex among diseased and healthy populations

Serum alkaline phosphatase-immunoglobulin complex was surveyed by polyacrylamide gel electrophoresis. Its frequency among apparently healthy blood donors was 1/3,015 or 0.03%. A significantly higher frequency, 8/2,400 or 0.33%, was observed among patients under 60 years of age. There was an apparently age related, sharp increase among patients over 60 years.